PREVAIL Trial Summary

A copy of our full protocol can be found here.

 

The PREVAIL study is a national study organised by the University College London and is funded by the Department of Health (Health Technology Assessment programme).

Many babies admitted to neonatal intensive care need fluids and medicines given to them through their veins. This is done via a very narrow tube placed through the skin of the arm or leg and into a central vein. This tube is called a peripherally inserted central catheter (PICC). A PICC can also be referred to as a ‘long line’. Babies in neonatal units often need to take medicines and fluids through PICCs for a long time. PICCs are inserted in order to avoid the need for repeated painful procedures and can stay in place for several weeks. However, very occasionally these PICCs can cause infections in the blood.

There are currently two types of PICCs available. One type is coated with an antibiotic and an antifungal which might prevent infection by killing bacteria (AM-PICC), and the other type is not (a standard PICC). 

Although both are available, neonatal units tend to use the standard PICC (S-PICC) and this will probably not change unless a study shows that AM-PICCS are superior. This study will help hospitals to decide which type of PICC to use for babies admitted to neonatal intensive care in the future.

This study will help hospitals to decide which type of PICC to use for babies admitted to neonatal intensive care in the future.
In order to do this, this study will take place across 18 neonatal units in the UK and over 850 babies will participate over 2 years.

If you are a parent and would like more information about the trial please see our Parents section.

 




I'm fine with this [X]

The site uses cookies, some may have been set already. Please refer to our privacy policy & cookie usage statement.
If you continue to use the site we'll assume you're happy to accept the cookies.